Popular

BPC 157 (10mg) + TB 500 (10mg) Blend

20mg | Third-Party Tested | 99% Purity | COA Available | Research Use Only

The BPC-157 + TB-500 Blend adds two widely researched synthetic peptides in an equal ratio, i.e., 1:1 (10mg BPC-157 + 10mg TB-500 per vial).

$147.00

0 out of 5 · 0 ratings

Be the first to rate this compound:

Out of stock

Buy BPC-157 10mg + TB-500 10mg (Blend)

The BPC-157 + TB-500 Blend adds two widely researched synthetic peptides in an equal ratio, i.e., 1:1 (10mg BPC-157 + 10mg TB-500 per vial). BPC-157 is a stable 15-amino-acid fragment obtained from the protein of human gastric juice, while TB-500 is a synthetic variant of the active domain of Thymosin Beta-4. The synergistic effects of this combination on tissue repair, angiogenesis, cell migration, inflammation modulation, and regenerative biology are being researched in preclinical models. Each vial is delivered as a clean and lyophilized powder made in the USA that is ≥99% pure (HPLC-verified). The pre-mixed format makes reconstitution simple and supports efficient dosing in in vitro assays, cell culture, or animal injury models. This blend is used exclusively for in vitro and in vivo laboratory research, and it is not for human consumption, therapeutic use, veterinary application, or any non-research purpose. For research use only. Strictly not for human consumption.

Biochemical Characteristics

BPC-157

Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Molecular formula: C₆₂H₉₈N₁₆O₂₂
Molecular weight: 1419.55 Da
Stable in gastric juice; high resistance to enzymatic degradation

TB-500 (Thymosin Beta-4 fragment)

Active domain: Ac-LKKTETQ
Molecular formula: C₃₈H₆₈N₁₀O₁₄
Molecular weight: ≈889 Da
Regulates actin polymerization and cytoskeletal dynamics

The blend is provided as a single lyophilized acetate salt powder. The 10mg/10mg ratio helps the researchers to find out an additive or synergistic relation between gastric-derived cytoprotection and actin-binding repair pathways.

Research Application

In preclinical studies, the BPC-157 + TB-500 combination is used to:

Accelerate the healing of soft musculoskeletal tissues, for example, ligaments, muscles, and tendons.
To study the activity of fibroblasts, deposition of collagen, and angiogenesis.
Model reduction of edema and inflammation in ischemia-reperfusion or injury settings
To see the formation of granulation tissue, closure of the wound, and biomechanical healing.
To study the comparison of systemic and localized effects in models of severe lesions or tendon-to-bone integration.
Function as a helpful tool for peptide-mediated cytoprotection, sports medicine models, and regenerative biology.

Comparative research and continuous dosing are supported by the pre-blended vial without the need for customized reconstitutions.

Mechanism Overview

BPC-157 increases growth factors (VEGF, FGF), FAK-paxillin signaling, and also changes the pathways of nitric oxide. While promoting angiogenesis, collagen organization, and the balance of anti-inflammatory cytokines, it keeps endothelial integrity. Actin monomers are attached by TB-500, which also sequesters G-actin and promotes F-actin assembly. While promoting angiogenesis and decreasing inflammation through a number of mechanisms, it supports cell migration, differentiation, and cytoskeletal remodeling. Together, these two ( TB-500 and BPC-157) improve motility, structural reorganization, growth factors, and cytoprotection. Preclinical evidence suggests that fibroblast recruitment, vascularization, and tissue remodeling work together to improve functional recovery in injury models.

Preclinical Research Summary

Preclinical research demonstrates that BPC-157 enhances tendon, ligament, and muscle healing, specifically in rodent models. In Achilles transection and ligament injury models, it counteracts corticosteroid impairment, elevates collagen deposition, and increases biomechanical strength. TB-500 supports migration of cells, angiogenesis, and actin dynamics in wound and soft-tissue restoration. In animal research, combined use shows improved results:

Quicker formation of granulation tissue and wound closure
Decreased edema and inflammation
Better tendon-to-bone integration and ligament tensile load
Systemic effects on the protection of distant organs, such as the liver and kidney in ischemia-reperfusion.

Systematic reviews show that more than 35 preclinical studies regularly produced positive histological and functional results, with no toxicity found in safety evaluations. The mixture is being studied for musculoskeletal regeneration, but the human data is still not enough.

Form and Analytical Testing

Form: Sterile, lyophilized powder blend (10mg BPC-157 + 10mg TB-500)
Purity: ≥99% (HPLC for each peptide)
Identity: Confirmed by mass spectrometry
Endotoxin: <0.1 EU/μg
Solubility: Excellent in bacteriostatic water
Appearance: White to off-white cake
Storage (unopened): 2–8°C, protected from light and moisture
Reconstitution: Use sterile bacteriostatic water under aseptic conditions
Stability: Stable 24–36 months refrigerated when sealed; reconstituted stable 4–6 weeks at 2–8°C (avoid repeated freeze-thaw)

All batches undergo third-party analytical testing for purity, identity, and contaminants.

Referenced Citations

Sikiric P, et al. (2018). Stable gastric pentadecapeptide BPC 157 may recover brain-gut axis and gut-brain axis function. Pharmaceuticals.
Chang CH, et al. (2014). Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts. Molecules.

doi:10.3390/molecules191119066.

Vasireddi N, et al. (2025). Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review. HSS Journal. PMC12313605.
Krivic A, et al. (2006). Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: Promoted tendon-to-bone healing. Journal of Orthopaedic Research. doi:10.1002/jor.20109.
Malinda KM, et al. (1999). Thymosin β4 accelerates wound healing. Journal of Investigative Dermatology.

RUO Disclaimer

The BPC-157 + TB-500 Blend (10mg/10mg) is an investigational research compound intended solely for in vitro laboratory research and in vivo animal studies. It is not approved by the FDA, EMA, or any regulatory authority for human therapeutic use, diagnosis, treatment, or supplementation. It is classified as a research chemical (WADA S0 non-approved substances category), and preclinical findings do not predict human outcomes; no claims are made regarding safety or efficacy in humans. Compounds may carry risks, including immunogenicity or impurities. If mishandled, it should be handled only in qualified research facilities with institutional biosafety oversight. All sales are for laboratory research use only; not for human or veterinary consumption.

Research Use Only

This compound is intended for laboratory research use only. It is not intended for human or animal consumption, or for use in diagnostic or therapeutic procedures.

Chemical Properties

Property	BPC-157	TB-500
Molecular Formula	C62H98N16O22	C212H350N56O78S
Molecular Mass	1419.5 g/mol	4963 g/mol
Monoisotopic Mass	1418.70415882 Da	4960.4863169 Da
Polar Surface Area	573 Å²	2250 Å²
Molecular Complexity	3040	12,200
XLogP	−9	−43.5
Heavy Atom Count	100	347
Hydrogen Bond Donors	16	72
Hydrogen Bond Acceptors	24	88
Rotatable Bonds	39	180
PubChem CID	9941957	16132341
InChIKey	HEEWEZGQMLZMFE-RKGINYAYSA-N	UGPMCIBIHRSCBV-XNBOLLIBSA-N
SMILES	C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)…	CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)…

Certificate of Analysis

Quality

Every batch of BPC 157 (10mg) + TB 500 (10mg) Blend is tested for purity and identity using industry-standard methods.

HPLC Analysis

High-Performance Liquid Chromatography confirms purity ≥99%. Each batch is analyzed to ensure consistent quality.

Mass Spectrometry (MS)

Identity verification via mass spectrometry confirms correct molecular weight of 4113.58 g/mol.

Third-Party Testing

All compounds undergo independent third-party laboratory testing for quality assurance.

Request COA

Certificate of Analysis documents are available for all compounds. Contact us with your order number to request batch-specific documentation.

COA Lab Tests

Each compound batch is tested by independent laboratories to verify purity, identity, and quality. The Certificate of Analysis (COA) provides transparent lab results, ensuring the compound meets strict research-grade standards.

Storage & Handling

Be‍fore Reconstitu⁠tion (P‌owder Form)

Long-T‍erm Storag‍e

Store at -2‌0°C or -4°F o‌r below
Ca⁠n remain stable for extended periods when fr‌ozen

Short-Term Sto⁠rage

R‌efrigerate at 2-‌8°C or 36-46°F for up to 4 weeks
Stable at room temper‌a‍tu‍re‌ for 3 weeks maximum
Cold storage‍ recommended for‌ best results
Avoid st‍oring i‍n refrigerato‌r door

After Reconstitution (Liquid Form)

Refrigerate im‌mediately at 2-8°C o‌r 36-46°F
St‌ore in main refrigerator c⁠ompartment
Do not‍ store in refrig‌erator door
Never leave at room temperature
Use with‌in 2-4 weeks of‍ reconstitution
For extended storage, fr‌eez‌e below -18⁠°C with carri‍er protein

Important St‍orage Precautions

Avoid repeated f⁠reeze-thaw cycles co⁠mpletely
Avoid any te‌mperature fluctuations⁠
Keep away from dire‌ct sunlight always‍
Add 0.1% HSA or⁠ BSA carrier⁠ protein‍ f‍or long-term storage

After Reconstitution (Liquid Form)

Refrigerate im‌mediately at 2-8°C o‌r 36-46°F
St‌ore in main refrigerator c⁠ompartment
Do not‍ store in refrig‌erator door
Never leave at room temperature
Use with‌in 2-4 weeks of‍ reconstitution
For extended storage, fr‌eez‌e below -18⁠°C with carri‍er protein

Add

Test	Method	Result	Specification
Identity	HPLC-DAD	BPC-157 / TB-500	BPC-157 / TB-500	Pass
Purity	HPLC-DAD	99.24	>99% by HPLC	Pass
Quantity	HPLC Analyte Concentration Curve Assay	10.15 / 10.44	10mg / 10mg	Pass
Endotoxins	LAL ELISA	0.152 EU/mL	≤ 0.5 EU/mL	Pass
Sterility	Pour Plate	No Growth	No Growth	Pass

BPC 157 (10mg) + TB 500 (10mg) Blend

Email when stock available

Buy BPC-157 10mg + TB-500 10mg (Blend)

Biochemical Characteristics

BPC-157

Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

Molecular formula: C₆₂H₉₈N₁₆O₂₂

Molecular weight: 1419.55 Da

TB-500 (Thymosin Beta-4 fragment)

Active domain: Ac-LKKTETQ

Molecular formula: C₃₈H₆₈N₁₀O₁₄

Molecular weight: ≈889 Da

Research Application

Mechanism Overview

Preclinical Research Summary

Form and Analytical Testing

Referenced Citations

RUO Disclaimer

Research Use Only

Chemical Properties

Certificate of Analysis

Quality

HPLC Analysis

Mass Spectrometry (MS)

Third-Party Testing

Request COA

COA Lab Tests

Storage & Handling

Be‍fore Reconstitu⁠tion (P‌owder Form)

Long-T‍erm Storag‍e

Short-Term Sto⁠rage

After Reconstitution (Liquid Form)

Important St‍orage Precautions

After Reconstitution (Liquid Form)

Related Compounds

Storage

Certificate of Analysis