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BPC-157 – 5mg

Name: BPC-157 - 5mg - Orion Peptides
Brand: Orion Peptides
Price: 60.00 USD
Availability: InStock

5mg | Third-Party Tested | 99% Purity | COA Available | Research Use Only

BPC-157, also known as Body Protection Compound-157, is a man-made pentadecapeptide with a 15-amino-acid chain.

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BPC-157

BPC-157, also known as Body Protection Compound-157, is a man-made pentadecapeptide with a 15-amino-acid chain. It is derived from a protective protein found in human gastric juice. This stable research compound is widely studied in preclinical laboratory settings, including in vitro cell cultures and animal models, mainly rodents, due to its potential cytoprotective, regenerative, and anti-inflammatory properties. BPC-157 is mainly used for research purposes within laboratories. It is not allowed for human consumption, therapeutic use, or veterinary application. It has no approval from regulatory agencies such as the FDA for human use and remains in the preclinical research phase.

BPC-157 5MG

BPC-157 5MG is a vial containing 5 milligrams of the lyophilized peptide. It is commonly used in controlled laboratory experiments where lower concentrations are required. This quantity allows researchers to prepare solutions at different dilutions for in vitro assays, such as cell migration studies, or in vivo dosing in animal models, enabling precise titration in preclinical investigations.

How BPC-157 Works in Preclinical Models

In experimental research, BPC-157 acts in a pleiotropic manner by influencing several major signaling pathways. Studies indicate activation of VEGFR2 and downstream Akt-eNOS pathways, contributing to nitric oxide production and angiogenesis in both cellular and animal models. It also enhances FAK-paxillin signaling related to cell migration and survival, upregulates growth hormone receptor expression, and affects JAK-2 pathways. Additionally, BPC-157 may modulate inflammatory responses by reducing pro-inflammatory mediators such as Nos2 and Nfkb while supporting anti-inflammatory processes. These mechanisms are observed under controlled in vitro and in vivo experimental conditions where the peptide interacts with cellular and tissue systems.

BPC-157 and Recovery Support in Research Models

Preclinical animal studies using induced injury models have examined the role of BPC-157 in tissue recovery processes. Research findings demonstrate improved healing responses in musculoskeletal models, including tendon transection, ligament rupture, and muscle injury. Improvements in collagen organization, fibroblast activity, and biomechanical strength have also been observed.

BPC-157 and Digestive Balance in Research Models

BPC-157 has been evaluated in extensive preclinical studies involving rodent gut injury models such as NSAID-induced damage, ulcers, and inflammation. Laboratory findings suggest support for mucosal integrity, reduced lesion severity, and improved epithelial healing through angiogenesis and inflammation modulation.

BPC-157 and Tissue Support in Research Models

BPC-157 has also been studied in animal and cell culture research for its interaction with connective tissues including muscles, ligaments, and bones. Experimental observations indicate stimulation of fibroblast proliferation, collagen production, and tissue remodeling responses following injury or stress.

Choosing the Right BPC-157 Strength for Laboratory Use

BPC-157 is available in 5MG and 10MG vials to meet different research requirements. The 5MG option is suitable for lower-dose or titration-based studies, while 10MG vials may be preferred for larger-scale or extended experimental protocols.

How to Store and Handle BPC-157 Safely in the Laboratory

BPC-157 peptides should be stored in a dry, frozen environment protected from sunlight and temperature fluctuations. During reconstitution and handling, aseptic laboratory techniques and appropriate personal protective equipment (PPE) should always be used.

Intended Use & Disclaimer

BPC-157 is a research-grade peptide intended strictly for in vitro and in vivo laboratory research purposes. The compound is not approved by the FDA for human therapeutic use. The World Anti-Doping Agency classifies this compound as prohibited without authorized application. Results obtained from preclinical studies cannot be directly applied to humans. Human research remains limited, and potential risks such as immunogenicity may exist when sourced from unregulated materials. All information provided is for research and educational purposes only.

Referenced Citations

Krivic A, et al. (2006). Achilles detachment in rat and stable gastric pentadecapeptide BPC 157. Journal of Orthopaedic Research.
Cerovecki T, et al. (2010). Pentadecapeptide BPC 157 improves ligament healing. Journal of Orthopaedic Research.
Vasireddi N, et al. (2025). Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review. HSS Journal.
Xu C, et al. (2020). Preclinical safety evaluation of body protective compound-157. Regulatory Toxicology and Pharmacology.
Sikiric P, et al. (2013). Toxicity by NSAIDs counteracted by stable gastric pentadecapeptide BPC 157. Current Pharmaceutical Design.
Additional insights from PubMed-indexed preclinical studies on musculoskeletal, gastrointestinal, and cytoprotective effects.

Research Use Only

This compound is intended for laboratory research use only. It is not intended for human or animal consumption, or for use in diagnostic or therapeutic procedures.

Chemical Properties

Molecular Formula	C62H98N16O22
Molecular Mass	1419.5 g/mol
Monoisotopic Mass	1418.70415882 Da
Polar Area	573 Å²
Complexity	3040
XLogP	-9
Heavy Atom Count	100
Hydrogen Bond Donor Count	16
Hydrogen Bond Acceptor Count	24
Rotatable Bond Count	39
CID	9941957
InChI	InChI=1S/C62H98N16O22/c1-31(2)25-37(55(92)74-50(32(3)4)62(99)100)71-46(81)29-65-51(88)33(5)67-53(90)38(26-48(84)85)73-54(91)39(27-49(86)87)72-52(89)34(6)68-57(94)41-15-10-21-75(41)58(95)35(13-7-8-20-63)70-45(80)30-66-56(93)40-14-9-22-76(40)60(97)43-17-12-24-78(43)61(98)42-16-11-23-77(42)59(96)36(18-19-47(82)83)69-44(79)28-64/h31-43,50H,7-30,63-64H2,1-6H3,(H,65,88)(H,66,93)(H,67,90)(H,68,94)(H,69,79)(H,70,80)(H,71,81)(H,72,89)(H,73,91)(H,74,92)(H,82,83)(H,84,85)(H,86,87)(H,99,100)/t33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,50-/m0/s1
InChIKey	HEEWEZGQMLZMFE-RKGINYAYSA-N
IUPAC Name	(4S)-4-[(2-aminoacetyl)amino]-5-[(2S)-2-[(2S)-2-[(2S)-2-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-3-carboxy-1-[[(2S)-3-carboxy-1-[[(2S)-1-[[2-[[(2S)-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-5-oxopentanoic acid
SMILES	C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCCN3C(=O)[C@@H]4CCCN4C(=O)[C@H](CCC(=O)O)NC(=O)CN

Certificate of Analysis

Quality

Every batch of BPC-157 – 5mg is tested for purity and identity using industry-standard methods.

HPLC Analysis

High-Performance Liquid Chromatography confirms purity ≥99%. Each batch is analyzed to ensure consistent quality.

Mass Spectrometry (MS)

Identity verification via mass spectrometry confirms correct molecular weight of 4113.58 g/mol.

Third-Party Testing

All compounds undergo independent third-party laboratory testing for quality assurance.

Request COA

Certificate of Analysis documents are available for all compounds. Contact us with your order number to request batch-specific documentation.

COA Lab Tests

Each compound batch is tested by independent laboratories to verify purity, identity, and quality. The Certificate of Analysis (COA) provides transparent lab results, ensuring the compound meets strict research-grade standards.

Storage & Handling

Before Reconstitu‍tion (Powde‌r Form)

Store in des‍iccated conditio‍ns below -80°C for long‌-term storage
Keep i‍n original sealed conta‍iner
Protect f‌rom moisture and humidity

After Reconstitution (⁠Liquid Form)‍

Store at 4°C for 2-7‍ days only
F‍or extended use, stor‌e below -80°C
Use 0.1% HSA‌ or B‍SA as carrie‍r protein

Important Storage Pr‍ecautions

Always preven‌t freeze-thaw cycles
D⁠o not repeated‌ly fr‍e⁠eze‌ and thaw
Ke⁠ep away from direct light expos‍ure
Store in sterile conditions a‍t all times
L⁠a‍bel with‍ reco⁠ns⁠ti⁠tution⁠ date
Do not shake vigorously

After Reconstitution (⁠Liquid Form)‍

Store at 4°C for 2-7‍ days only
F‍or extended use, stor‌e below -80°C
Use 0.1% HSA‌ or B‍SA as carrie‍r protein

Test	Method	Result	Specification
Identity	HPLC-DAD	BPC-157	BPC-157	Pass
Purity	HPLC-DAD	99.17	>99% by HPLC	Pass
Quantity	HPLC Analyte Concentration Curve Assay	5.08	5mg	Pass
Endotoxins	LAL ELISA	0.161 EU/mL	≤ 0.5 EU/mL	Pass
Sterility	Pour Plate	No Growth	No Growth	Pass

BPC-157 – 5mg

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BPC-157

BPC-157 5MG

How BPC-157 Works in Preclinical Models

BPC-157 and Recovery Support in Research Models

BPC-157 and Digestive Balance in Research Models

BPC-157 and Tissue Support in Research Models

Choosing the Right BPC-157 Strength for Laboratory Use

How to Store and Handle BPC-157 Safely in the Laboratory

Intended Use & Disclaimer

Referenced Citations

Research Use Only

Chemical Properties

Certificate of Analysis

Quality

HPLC Analysis

Mass Spectrometry (MS)

Third-Party Testing

Request COA

COA Lab Tests

Storage & Handling

Before Reconstitu‍tion (Powde‌r Form)

After Reconstitution (⁠Liquid Form)‍

Important Storage Pr‍ecautions

After Reconstitution (⁠Liquid Form)‍

Related Compounds

Storage

Certificate of Analysis