Tesamorelin is a synthetic 44-amino-acid analog of growth hormone–releasing hormone (GHRH), with a modification at its N-terminus. Orion Peptides supplies tesamorelin as a lyophilized research compound for in-vitro and analytical work only. It is not for human or veterinary use.
If you are sourcing tesamorelin for a study, the COA is the document that matters most. Here is how to judge one.
Why a 44-residue peptide needs more than a purity number
The longer a sequence, the more ways synthesis can go slightly wrong: a missing residue, an incomplete coupling, an unmodified N-terminus. These variants can co-elute near the main HPLC peak. That’s why a separate identity test, ideally mass spectrometry, matters as much as the purity figure. FDA guidance on synthetic peptides makes the same point: the profile of peptide-related impurities matters, not just the total (FDA).
Tesamorelin COA checklist
| On the certificate | Why it matters |
|---|---|
| HPLC purity + chromatogram | Shows the main peak and impurity peaks, not just a number |
| Identity test (mass spec, or HPLC vs a reference standard) | Confirms the peptide is tesamorelin |
| Net peptide content (mg) | Confirms how much peptide is actually in the vial |
| Testing lab name | Lets you confirm the report exists |
| Batch number + test dates | Ties the report to a specific production batch |
For a full walkthrough, read How to Read a Peptide COA and our 7-point COA credibility check.
Orion Peptides tesamorelin
Every Orion Peptides batch is tested by a third-party laboratory, Hyte Research Division. Certificates are on our COA Verification page.
For the science behind the compound, see Tesamorelin: A Complete Scientific Overview, Tesamorelin’s GHRH Mechanism and Tesamorelin vs Ipamorelin.
Storage basics for lyophilized tesamorelin
Keep vials sealed, dry and cold, and protect them from light. Avoid repeated temperature cycling. Record the receipt date and storage conditions with your study notes. Reconstitution for in-vitro work should follow your lab’s own protocol.
Shop: Orion Peptides tesamorelin
FAQ
Is tesamorelin for human use? Orion Peptides tesamorelin is a research compound for laboratory use only. It is not a medicine.
How long is tesamorelin’s sequence? 44 amino acids, based on the GHRH sequence with an N-terminal modification.
Can I see the COA before ordering? Yes. Visit COA Verification or contact Orion Peptides support.
Relevant resources
- FDA — Synthetic peptide guidance (impurity characterization), May 2021
- ISO/IEC 17025:2017 — competence of testing laboratories
- PepIndex — September 2026 analysis of 664 peptide certificates
All Orion Peptides compounds are for research use only. Not for human or veterinary use.
