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DSIP 10mg

| Third-Party Tested | 99% Purity | COA Available | Research Use Only

Delta Sleep Inducing Peptide (DSIP) is a synthetic nonapeptide studied in laboratory conditions for decades in relation to sleep regulation, stress response, and neuroendocrine modulation.

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Buy DSIP(Delta Sleep-Inducing Peptide)  10 mg

DSIP stands for Delta Sleep-Inducing Peptide. It is a naturally occurring small neuropeptide. It was first discovered in the 1970s in brain extracts. It was discovered by a Swiss research team, and its consist of 9 amino acids. It was first thought to help regulate sleep. However, later studies showed mixed and conflicting results. So its exact role in sleep is still not clear.

DSIP 10mg Molecular Structure and Chemical Properties

DSIP (Delta Sleep-Inducing Peptide), also known as Emideltide, is a synthetic nonapeptide containing nine amino acids. Researchers study DSIP to investigate sleep regulation, slow-wave sleep, stress responses, and neuroendocrine signaling.

DSIP Chemical Properties Table

Property Correct Information
Compound Name Delta Sleep-Inducing Peptide (DSIP)
Alternative Name Emideltide
Molecular Formula C₃₅H₄₈N₁₀O₁₅
Molecular Weight 848.8 g/mol
CAS Number 62568-57-4
PubChem CID 68816
Amino Acid Length 9 amino acids
Amino Acid Sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
One-Letter Sequence WAGGDASGE
Peptide Classification Synthetic nonapeptide
Peptide Structure Linear
Disulfide Bonds None
N-Terminal Group Free amino group
C-Terminal Group Free carboxyl group
Monoisotopic Mass 848.3301 Da
Research Applications Sleep architecture, slow-wave sleep, stress responses, and neuroendocrine signaling
Compound Size 10mg
Source: PubChem – DSIP Chemical Properties

Medical Literature About DSIP

Delta Sleep-Inducing Peptide has been studied by scientists since the 1970s. It is a small peptide made of 9 amino acids. At first, researchers thought it might help control sleep, especially deep sleep called slow-wave sleep. Early studies on animals showed that it could increase deep sleep activity and affect brain signals. It was also thought to have an effect on body rhythms, hormones, and stress responses. Later reviews concluded that DSIP shows a wide range of physiological effects, including possible impacts on:
  • Neurotransmitter activity
  • Hormonal regulation (cortisol, stress response systems)
  • Circadian rhythm modulation
  • Pain threshold and autonomic functions
Despite this, modern research has not confirmed a clear or reliable sleep-inducing mechanism. Because of this, DSIP is still considered a research peptide with unclear clinical significance rather than an established therapeutic agent.

References

  1. Schoenenberger GA, et al. Delta sleep-inducing peptide (DSIP): the state of Art. Eur Neurol. 1984;23(5):321-329.
  2. Graf MV, et al. A review of delta sleep-inducing peptide (DSIP). Neurosci Biobehav Rev. 1985;9(3):397-412.
  3. Kovalzon VM, et al. Effects of DSIP on sleep and other physiological functions: a review. Neurosci Behav Physiol. 2009;39(3):227-234.
  4. Yehuda S, et al. A review of DSIP effects on sleep, stress and pain. Peptides. 2007;28(3):622-629.
  5. Bjorvatn B, et al. 

Research Use Only

This compound is intended for laboratory research use only. It is not intended for human or animal consumption, or for use in diagnostic or therapeutic procedures.

Chemical Properties

Molecular Formula C35H48N10O15
Molecular Mass 848.8 g/mol
Monoisotopic Mass 848.33006086 Da
Polar Area 407 Ų
Complexity 1610
XLogP -7.1
Heavy Atom Count 60
Hydrogen Bond Donor Count 14
Hydrogen Bond Acceptor Count 16
Rotatable Bond Count 25
CID 68816
InChI InChI=1S/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)/t16-,17-,20-,22-,23-,24-/m0/s1
InChIKey ZRZROXNBKJAOKB-GFVHOAGBSA-N
IUPAC Name (2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]acetyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]pentanedioic acid
Smiles C[C@@H](C(=O)NCC(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)N

Certificate of Analysis

Quality

Every batch of DSIP 10mg is tested for purity and identity using industry-standard methods.

HPLC Analysis

High-Performance Liquid Chromatography confirms purity ≥99%. Each batch is analyzed to ensure consistent quality.

Mass Spectrometry (MS)

Identity verification via mass spectrometry confirms correct molecular weight of 4113.58 g/mol.

Third-Party Testing

All compounds undergo independent third-party laboratory testing for quality assurance.

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Certificate of Analysis documents are available for all compounds. Contact us with your order number to request batch-specific documentation.

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COA Lab Tests

Each compound batch is tested by independent laboratories to verify purity, identity, and quality. The Certificate of Analysis (COA) provides transparent lab results, ensuring the compound meets strict research-grade standards.

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Storage & Handling

Before Reconstitution (Powder Form)

  • Store in the refrigerator at 2°C – 8°C.
  • For long-term storage, keep it in the freezer at -20°C.
  • Protect from heat, moisture, and direct light.
  • Keep the vial in a dry, cool place.

After Reconstitution (Mixed With Bacteriostatic Water)

  • Store in the refrigerator at 2°C – 8°C.
  • Shelf life is 2–4 weeks after mixing.
  • Do not freeze after mixing (liquid form becomes unstable).

General Tips

  • Avoid repeated freeze-thaw cycles.
  • Always wipe the vial top with an alcohol swab before use.
  • Keep it in the original vial to avoid contamination.

After Reconstitution (Mixed With Bacteriostatic Water)

  • Store in the refrigerator at 2°C – 8°C.
  • Shelf life is 2–4 weeks after mixing.
  • Do not freeze after mixing (liquid form becomes unstable).

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Certificate of Analysis

ORP#00034
Client:
Orion Peptides
Sample:
DSIP - 10mg
Batch:
202606DS10
Tests Requested:
Standard + Endotoxins + Sterility
Appearance:
White Lyophilized Powder in 3mL Vial
Analysis Conducted on:
06/02/2026
Report Issued on:
08/01/2026
Test Method Result Specification  
Identity HPLC-DAD DSIP DSIP Pass
Purity HPLC-DAD 99.87 >99% by HPLC Pass
Quantity HPLC Analyte Concentration Curve Assay 12.3 10mg Pass
Endotoxins LAL ELISA 0.122 EU/mL ≤ 0.5 EU/mL Pass
Sterility Pour Plate No Growth No Growth Pass
Disclaimer: The data contained in this report is representative of the received sample. This analysis is for informational purposes only. The tested substances are intended for research use only and are not approved for human or veterinary use, diagnostic, therapeutic, or clinical applications. All data was obtained under standard laboratory conditions.
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