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GHK-Cu – 10mg

| Third-Party Tested | 99% Purity | COA Available | Research Use Only

GHK‑Cu is a small peptide that naturally binds copper. It is found in human blood, saliva, and urine. In the lab, researchers use it to see how cells respond to copper and small peptides.

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GHK-Cu – 10mg

GHK-Cu is a small cosmetic peptide that naturally binds copper. It is found in human blood, saliva, and urine. In the lab, researchers use it to study how cells respond to copper and small peptides. This peptide is not a drug or supplement. It is intended strictly for research use. Scientists investigate how it interacts with cells, proteins, and other molecules, examining its effects on biochemical pathways and cellular processes. Buy GHK-Cu – 10 mg Now at Orion Peptides

Biochemical Characteristics of GHK-Cu Peptide

GHK-Cu peptide consists of three amino acids: glycine, histidine, and lysine. When it binds copper, it becomes GHK-Cu.
  • Amino acid sequence: Gly-His-Lys
  • Molecular formula: C14H24N6O4Cu
  • Molecular weight: ~340.3 g/mol
In laboratory studies, researchers monitor how GHK-Cu binds copper and how the complex behaves in cells. They also observe changes in proteins, enzymes, and other markers when added to experimental systems.

Research Applications of GHK-Cu

Researchers add GHK-Cu to cells and observe biological responses over time. Experiments may evaluate cell growth, gene expression, protein/enzyme activity, and copper-mediated processes in cells. Results vary depending on cell type, tissue model, peptide concentration, and experimental design. Each study may show slightly different outcomes. These studies aim to observe basic chemical and cellular behavior, not clinical or applied effects.

Mechanistic and Pathway Context

GHK-Cu interacts with cellular components sensitive to copper. This may influence intracellular copper processing. Researchers observe effects on cell signaling, protein function, and gene activity over time in controlled lab settings. Some studies also examine tissue-level responses in experimental models. All work is preclinical and exploratory.

Preclinical Research Summary

Preclinical studies use cell or animal models to evaluate GHK-Cu activity in the lab. Researchers often measure copper levels, enzyme activity, and cellular responses. They also monitor protein or gene changes upon peptide exposure. Results depend on the system, dose, and experimental setup. These studies are exploratory and are not intended to predict human effects.

Formulation and Analytical Testing

GHK-Cu is supplied as a lyophilized powder, 50 mg per vial or 10 mg per vial, for precise laboratory experiments. Analytical verification typically includes:
  • Confirming identity
  • Testing purity
  • Verifying copper content
Store in a cool, dry place following standard laboratory safety protocols. Not intended for injection or human use. Buy GHK-Cu – 10 mg Now at Orion Peptides

References

Pickart L, Thaler MM: Copper peptide in human plasma. Science. 1973;180(4088):868–870. Hong SJ, Kang SS, Dan DH: Effects of copper-peptide complexes on cultured cells: biochemical modulation studies. Pickart L: Peptide-copper complexes and gene expression modulation. Mol Cell Biochem. 2006;286(1–2):1–15.

Research Use Only

This compound is intended for laboratory research use only. It is not intended for human or animal consumption, or for use in diagnostic or therapeutic procedures.

Chemical Properties

Molecular Formula C28H48CuN12O8
Molecular Weight 744.3 g/mol
Monoisotopic Mass 743.301404 Da
Polar Surface Area 352 Ų
Complexity 952
XLogP N/A
Heavy Atom Count 49
Hydrogen Bond Donors 12
Hydrogen Bond Acceptors 14
Rotatable Bonds 22
CID 133697840
InChI InChI=1S/2C14H24N6O4.Cu/c2*15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;/h2*7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24);/t2*10-,11-;/m00./s1
InChIKey RIPDSRHLQNAZOH-XTQNZXNBSA-N
IUPAC Name bis((2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid);copper
SMILES C1=C(NC=N1)C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)CN.C1=C(NC=N1)C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)CN.[Cu]

Certificate of Analysis

Quality

Every batch of GHK-Cu – 10mg is tested for purity and identity using industry-standard methods.

HPLC Analysis

High-Performance Liquid Chromatography confirms purity ≥99%. Each batch is analyzed to ensure consistent quality.

Mass Spectrometry (MS)

Identity verification via mass spectrometry confirms correct molecular weight of 4113.58 g/mol.

Third-Party Testing

All compounds undergo independent third-party laboratory testing for quality assurance.

Request COA

Certificate of Analysis documents are available for all compounds. Contact us with your order number to request batch-specific documentation.

COA Lab Tests

Each compound batch is tested by independent laboratories to verify purity, identity, and quality. The Certificate of Analysis (COA) provides transparent lab results, ensuring the compound meets strict research-grade standards.

Storage & Handling

Before Reconsti‍tution (Powder⁠ Form)‌

  • Store at -20°C or lower in the freezer
  • Keep in lyophilize‍d form for stabil⁠i⁠ty
  • Mainta‍in consist‌ently cold te‍mperature
  • Protect f‍rom light exposure at⁠ all times
  • Keep away f‌rom⁠ moistur⁠e
  • Store‍ in sealed‌, air⁠tigh⁠t container
  • Use ligh‍t-resist‍a⁠nt packag⁠ing‍

Aft⁠er Recon‌stitutio‌n (L‍iquid Fo‌rm)

  • Use promptly afte⁠r reconstitution when possible
  • Store at 4°C‍ for short-term u‌se only‍
  • Keep refrigerated between us⁠es
  • Limit storage duratio‍n for‌ optimal bioactivity

Travel and Transport

  • Us‍e insulated cooler or bag⁠ for⁠ travel
  • Inc‍lude ice pa⁠cks to maintain cold temperature
  • Avoid d⁠irect contact between pept‍ide and i⁠ce
  • Monitor temperature during transport
  • Keep in origi‍n‍al seale⁠d container

Aft⁠er Recon‌stitutio‌n (L‍iquid Fo‌rm)

  • Use promptly afte⁠r reconstitution when possible
  • Store at 4°C‍ for short-term u‌se only‍
  • Keep refrigerated between us⁠es
  • Limit storage duratio‍n for‌ optimal bioactivity

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Storage

Store at -20°C.
Protect from light and moisture.

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Certificate of Analysis

ORP#00045

Client:
Orion Peptides
Sample:
GHK-Cu 10mg
Batch:
202609GHKCU10

Tests Requested:
Standard + Endotoxins + Sterility
Appearance:
Blue Lyophilized Powder in 3mL Vial

Analysis Conducted on:
09/03/2026
Report Issued on:
09/04/2026
Test Method Result Specification  
Identity HPLC-DAD GHK-Cu GHK-Cu Pass
Purity HPLC-DAD 99.14 >99% by HPLC Pass
Quantity HPLC Analyte Concentration Curve Assay 10.06 10mg Pass
Endotoxins LAL ELISA 0.050 EU/mL ≤ 0.5 EU/mL Pass
Sterility Pour Plate No Growth No Growth Pass