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Klow Blend – BPC 157 (10mg) + TB 500 (10mg) + GHK-Cu (50mg) + KPV (10mg) Blend

| Third-Party Tested | 99% Purity | COA Available | Research Use Only

The BPC-157 / TB-500 / GHK-Cu / KPV Research Blend, also known as Klow Blend, is a synthetically formulated combination of four research peptides supplied in a single vial. Researchers can buy Klow Blend for laboratory research and study the individual properties and interactions of these peptide components under controlled experimental conditions.

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Buy Klow Blend 80mg

Klow Blend is a research peptide formulation that combines BPC-157, TB-500, GHK-Cu, and KPV in a single vial. Each peptide has its own unique molecular structure and biological properties. Researchers study these peptides to understand different cellular processes, signaling pathways, and molecular interactions. By combining them in one formulation, researchers can investigate how multiple peptide components behave within controlled laboratory research settings. Klow Blend is intended for research purposes only and is not intended for human use. Researchers can buy Klow Blend at Orion Peptides for laboratory research purposes.
Specification Details
Compound Name Klow Blend
Total Peptide Content 80 mg
BPC-157 10 mg
TB-500 10 mg
GHK-Cu 50 mg
KPV 10 mg
Form Lyophilized peptide blend
Packaging Single sealed vial
Intended Use Laboratory and in-vitro research only
Composition Ratio 50:10:10:10 mg
Research Focus Cellular signaling, peptide interactions, inflammatory pathways, extracellular matrix research, and cellular response

Klow Blend: Peptide Composition

Peptide Amount Research Focus
BPC-157 10 mg Studied in research involving tissue response, cellular signaling, and repair-related processes
TB-500 10 mg Investigated for cytoskeletal organization, cellular migration, and related biological processes
GHK-Cu 50 mg Researched for copper-binding activity, collagen synthesis, and extracellular matrix regulation
KPV 10 mg Studied for its interactions with inflammatory signaling pathways
Total Blend 80 mg Combined formulation for controlled laboratory and scientific research

Research Applications of Klow Blend

The Klow Blend combines BPC-157, TB-500, GHK-Cu, and KPV, allowing researchers to examine several peptide-related biological processes within a controlled experimental framework. The individual components have been investigated in areas including cellular migration, tissue-related signaling, inflammatory pathways, extracellular matrix activity, and molecular interactions. However, findings from studies of individual peptides should not be interpreted as evidence that the complete Klow Blend produces the same effects or has established synergistic activity.

1. Tissue and Cellular Response Studies

BPC-157 has been investigated in experimental models involving cellular migration, angiogenesis, collagen deposition, and tissue-related responses. For example, laboratory research has reported effects on endothelial cell proliferation and migration, as well as ERK1/2-related signaling.

Researchers may therefore study BPC-157 within controlled models to examine:

  • Cell migration and proliferation
  • Endothelial cell responses
  • Angiogenesis-related signaling
  • Collagen deposition
  • ERK1/2 signaling activity
  • Cellular responses to experimental stress

2. Cytoskeletal and Cell Migration Research

TB-500 is commonly described as a peptide fragment or derivative associated with thymosin β4 research. Much of the published literature concerns thymosin β4 itself rather than commercially supplied TB-500 preparations

Research involving this pathway may examine:

  • Actin filament organization
  • Cytoskeletal dynamics
  • Cell migration
  • Endothelial cell movement
  • Cellular adhesion
  • Migration-associated signaling

Studies have also investigated the relationship between thymosin β4 and matrix metalloproteinase activity during epithelial cell migration.

3. Inflammatory Pathway Research

KPV is the C-terminal tripeptide of α-MSH and has been investigated in several experimental inflammation models. Research has examined its effects on NF-κB signaling, inflammatory cytokine activity, and cellular inflammatory responses.

Research applications involving KPV may include:

  • NF-κB pathway analysis
  • Cytokine signaling studies
  • Inflammatory cell responses
  • MAP kinase pathway research
  • Epithelial cell signaling
  • Experimental models of intestinal inflammation

Importantly, much of the available evidence comes from cellular and animal models, so these findings should not be presented as established human effects.

4. Extracellular Matrix and Collagen Studies

GHK-Cu has been studied extensively in connection with fibroblast activity, collagen synthesis, and extracellular matrix regulation. Early in-vitro research found that GHK-Cu stimulated collagen synthesis in fibroblast cultures.

Additional research has examined its effects on extracellular matrix components and matrix-remodeling processes, including metalloproteinase expression.

Researchers may investigate GHK-Cu in relation to:

  • Collagen synthesis
  • Fibroblast activity
  • Extracellular matrix remodeling
  • Matrix metalloproteinases
  • Proteoglycan expression
  • Connective-tissue-related molecular processes

5. Multi-Peptide Interaction Analysis

Because Klow Blend contains four different peptide components, researchers can investigate how their individual molecular properties may interact within the same experimental system. Potential research areas include:

  • Peptide-to-peptide interactions
  • Changes in cellular signaling profiles
  • Comparative pathway analysis
  • Molecular response patterns
  • Independent versus combined peptide activity

Klow Blend vs. Individual Peptides

Research Material Composition General Research Focus
BPC-157 Single peptide Cellular signaling and migration-related research
TB-500 Single peptide Actin dynamics and cellular movement research
GHK-Cu Copper-binding peptide Collagen and extracellular matrix research
KPV Tripeptide Inflammatory signaling research
Klow Blend Four-peptide formulation Combined investigation of multiple peptide-related pathways

Klow Blend vs. Glow Blend

Klow Blend and Glow Blend share three of the same research peptides: BPC-157, TB-500, and GHK-Cu. The main difference is that Klow Blend contains KPV as a fourth component. Commonly listed formulations contain 70 mg in Glow Blend and 80 mg in Klow Blend.

Peptide Glow Blend Klow Blend General Research Area
BPC-157 10 mg 10 mg Cellular signaling and migration-related research
TB-500 10 mg 10 mg Cytoskeletal organization and cell migration research
GHK-Cu 50 mg 50 mg Collagen and extracellular matrix research
KPV — 10 mg Inflammatory signaling research
Total 70 mg 80 mg Multi-peptide research

Intended Research Use

This peptide blend is intended exclusively for laboratory and scientific research purposes.
  • In vitro experiments
  • Cell culture studies
  • Biochemical research protocols
  • Approved preclinical research models
All usage must comply with institutional research guidelines, ethical approvals, and applicable regulatory requirements.

Klow Blend Storage Guidelines

For research use, Klow Blend should be stored according to the supplier’s compound specifications and applicable laboratory protocols. General considerations include:

Storage Stage Recommended Practice
Before Reconstitution Keep the sealed vial in a cool, dry, temperature-controlled environment and protect it from direct light.
After Reconstitution Store the prepared research solution under appropriate refrigerated conditions and minimize unnecessary temperature changes.
Light Exposure Keep the vial protected from direct light and prolonged exposure to strong laboratory lighting.
Temperature Changes Avoid repeated freezing and thawing, as temperature cycling can affect peptide stability.
Container Keep the material in its original, properly sealed vial whenever possible.
Handling Use clean laboratory techniques and avoid unnecessary exposure to air, moisture, or contaminants.
Long-Term Storage Follow the manufacturer’s specific stability and storage information for long-term research storage.

Regulatory and Safety Disclaimer

This compound is supplied strictly for laboratory research use only. It is not approved by the FDA or any regulatory authority for human or veterinary use. The compound is intended solely for qualified research professionals operating within controlled scientific environments. No claims are made regarding safety, efficacy, or therapeutic application outside laboratory research. Users must comply with all applicable laws, institutional safety procedures, and ethical standards. Refer to the Material Safety Data Sheet (MSDS) and dispose of materials according to approved laboratory waste protocols. The supplier assumes no responsibility for misuse or improper handling.

Frequently Asked Questions

1. What is Klow Blend?

Klow Blend is a research peptide formulation containing BPC-157, TB-500, GHK-Cu, and KPV in a single vial.

2. How much peptide is in Klow Blend?

The formulation contains 80 mg of total peptide material: 10 mg BPC-157, 10 mg TB-500, 50 mg GHK-Cu, and 10 mg KPV.

3. What is Klow Blend studied for?

The individual components are studied across areas including cellular signaling, cell migration, inflammatory pathways, actin dynamics, collagen synthesis, and extracellular matrix activity.

4. Is Klow Blend intended for human use?

No. The compound is supplied for laboratory and scientific research purposes only and is not intended for human or veterinary use.

5. How should Klow Blend be stored?

Storage should follow the supplier’s compound-specific instructions and applicable laboratory protocols. Protect the material from unnecessary light, moisture, and temperature fluctuations.

KLOW Research Resources

Research References:

https://pubmed.ncbi.nlm.nih.gov/3169264/

https://pubmed.ncbi.nlm.nih.gov/18092346/

https://pubmed.ncbi.nlm.nih.gov/24382810/
 

Research Use Only

This compound is intended for laboratory research use only. It is not intended for human or animal consumption, or for use in diagnostic or therapeutic procedures.

Chemical Properties

Molecular Formula BPC-157: C62H98N16O22
TB-500: C212H350N56O78S
GHK-Cu: C28H48CuN12O8
KPV: C18H33N5O4
Molecular Mass BPC-157: 1419.5 g/mol
TB-500: 4963 g/mol
GHK-Cu: 744.3 g/mol
KPV: 383.5 g/mol
Monoisotopic Mass BPC-157: 1418.70415882 Da
TB-500: 4960.4863169 Da
GHK-Cu: 743.301404 Da
KPV: 383.25325455 Da
Polar Surface Area BPC-157: 573 Ų
TB-500: 2250 Ų
GHK-Cu: 352 Ų
KPV: 148 Ų
Molecular Complexity BPC-157: 3040
TB-500: 12200
GHK-Cu: 952
KPV: 552
XLogP (Lipophilicity) BPC-157: −9
TB-500: −43.5
GHK-Cu: Not available
KPV: −2.3
Heavy Atom Count BPC-157: 100
TB-500: 347
GHK-Cu: 49
KPV: 27
Hydrogen Bond Donors BPC-157: 16
TB-500: 72
GHK-Cu: 12
KPV: 4
Hydrogen Bond Acceptors BPC-157: 24
TB-500: 88
GHK-Cu: 14
KPV: 5
Rotatable Bonds BPC-157: 39
TB-500: 180
GHK-Cu: 22
KPV: 10
PubChem CID BPC-157: 9941957
TB-500: 16132341
GHK-Cu: 133697840
KPV: 9209049
InChIKey BPC-157: HEEWEZGQMLZMFE-RKGINYAYSA-N
TB-500: UGPMCIBIHRSCBV-XNBOLLIBSA-N
GHK-Cu: RIPDSRHLQNAZOH-XTQNZXNBSA-N
KPV: QZQBDQTYFDOVNN-KKUMJFAQSA-N
SMILES BPC-157:
C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCCN3C(=O)[C@@H]4CCCN4C(=O)[C@H](CCC(=O)O)NC(=O)CN

TB-500:
CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(C)C)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)C

GHK-Cu:
C1=C(NC=N1)C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)CN.C1=C(NC=N1)C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)CN.[Cu]

KPV:
CC(C)[C@@H](C(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)C

Certificate of Analysis

Quality

Every batch of Klow Blend – BPC 157 (10mg) + TB 500 (10mg) + GHK-Cu (50mg) + KPV (10mg) Blend is tested for purity and identity using industry-standard methods.

HPLC Analysis

High-Performance Liquid Chromatography confirms purity ≥99%. Each batch is analyzed to ensure consistent quality.

Mass Spectrometry (MS)

Identity verification via mass spectrometry confirms correct molecular weight of 4113.58 g/mol.

Third-Party Testing

All compounds undergo independent third-party laboratory testing for quality assurance.

Request COA

Certificate of Analysis documents are available for all compounds. Contact us with your order number to request batch-specific documentation.

COA Lab Tests

Each compound batch is tested by independent laboratories to verify purity, identity, and quality. The Certificate of Analysis (COA) provides transparent lab results, ensuring the compound meets strict research-grade standards.

Storage & Handling

Befor⁠e Reconstitution (Powder Fo‌rm)

For Long-T‌erm⁠ Storag⁠e

  • Store at -20°C or⁠ -4°F⁠ or bel⁠o‌w
  • Keep frozen for optimal‍ stability
  • Maintai‍n consistently fr⁠ozen t‍emperatur‌e

 

For Short-Te‌rm Storage

  • Refrigerate at -80°C (-112F)⁠

Afte⁠r Reconstitution (Li‌quid For‌m)

  • Refrig‍erate immediately at 2⁠–8‍°C or‌ 36–46°F
  • Store in the main refriger⁠ator compartment
  • Do not store in refrigerator doo‌r
  • Freeze below -18°C with carrier protein for extended storage

Important Storage Precautions

  • Avoid repeated freeze-tha‌w cycles complete⁠ly
  • Never leav‍e‌ at room temperature for extended period⁠s
  • ‌Ke‌ep away from dir‌ec‌t sunlight
  • Use⁠ ster⁠ile al⁠cohol swa‌bs on⁠ v‌ial t‌ops
  • A‌void direct con‌tact between vials and‍ ice

Afte⁠r Reconstitution (Li‌quid For‌m)

  • Refrig‍erate immediately at 2⁠–8‍°C or‌ 36–46°F
  • Store in the main refriger⁠ator compartment
  • Do not store in refrigerator doo‌r
  • Freeze below -18°C with carrier protein for extended storage

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Storage

Store at -20°C.
Protect from light and moisture.

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Certificate of Analysis

ORP#00035

Client:
Orion Peptides
Sample:
BPC-157 10mg + TB-500 10mg + GHK-Cu 50mg + KPV 10mg Blend (Klow)
Batch:
202609KLOW

Tests Requested:
Standard + Endotoxins + Sterility
Appearance:
White Lyophilized Powder in 10mL Vial

Analysis Conducted on:
09/02/2026
Report Issued on:
09/03/2026
Test Method Result Specification
Identity HPLC-DAD BPC-157 / TB-500 / GHK-Cu / KPV BPC-157 / TB-500 / GHK-Cu / KPV Pass
Purity HPLC-DAD 99.55 >99% by HPLC Pass
Quantity HPLC Analyte Concentration Curve Assay 10.19 / 10.38 / 50.94 / 10.10 10mg / 10mg / 50mg / 10mg Pass
Endotoxins LAL ELISA 0.119 EU/mL ≤ 0.5 EU/mL Pass
Sterility Pour Plate No Growth No Growth Pass